If you have puffy lips, you could be allergic to something in the Mestinon. Please consult with your doctor (today).

On that small of a dose, it shouldn't make you weaker if you have MG. I started out that small nine years ago and it made me feel much stronger.

If you can handle Benadryl, at smaller doses, it will counteract the Mestinon and take care of any allergic reaction (or possibly not take care of it if it's a bad one). Mestinon and Benadryl do the opposite thing to acetylcholine; Mestinon increases it and Benadryl can decrease it.

While I would be more than willing to give Susan (Desert Flower) credit for the anger/panic attack thing, it was actually me who brought it up.

Have your doctors thought about polymyositis? That's a possibility. I really hope you can figure out what is causing your symptoms - definitively that is.

Annie