pyridostigmine - cholinesterase iinhibitor like aricept.

Proband I, a 30-year-old woman of Ashkenazi Jewish origin and no significant history of adverse drug responses, received a single oral dose of 30 mg pyridostigmine, a dose considered safe, which is given prophylactically under anticipation of chemical warfare (12).

Within 1 h, peripheral blood AChE fell to an almost undetectable level, increasingly severe muscle fasciculations developed, accompanied by intense headache, rhinnorea, lacrimation and frequent urination. These acute symptoms continued for 3 days, and resolved into a 5-day period of extreme fatigue, muscle weakness and general malaise.

I hear ya!
Been there,
paula

http://hmg.oxfordjournals.org/cgi/content/full/9/9/1273