 |
Wisest Elder Ever
|
|
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
|
|
|
Wisest Elder Ever
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
|
Are you describing tarsal tunnel release, and carpal tunnel?
These are surgeries. Some people develop a chronic pain condition called RSD when the wrist or ankle is involved in a surgical procedure. I have lost count of how many come to our RSD forum with foot or ankle surgery and develop RSD.
If your BIL is really going thru with this, read this study:
Quote:
Lancet. 1999 Dec 11;354(9195):2025-8.
Effect of vitamin C on frequency of reflex sympathetic dystrophy in wrist fractures: a randomised trial.
Zollinger PE, Tuinebreijer WE, Kreis RW, Breederveld RS.
Department of Orthopaedics, Leyenburg Hospital, The Hague, The Netherlands.
Comment in:
* J Bone Joint Surg Am. 2007 Nov;89(11):2550-1; author reply 2551-2.
BACKGROUND: The pathogenesis of reflex sympathetic dystrophy (RSD) is not clear, nor is there a definitive treatment for this syndrome. The morbidity, costs in health care, and loss of work time justify the search for a means to prevent post-traumatic dystrophy. Although the role of toxic oxygen radicals has not yet been clarified, we investigated vitamin C (ascorbic acid) as a prophylactic antioxidant drug. METHODS: 123 adults with 127 conservatively treated wrist fractures were randomly allocated in a double-blind trial to take a capsule of 500 mg vitamin C or placebo daily for 50 days. Each participant's sex, age, side of fracture, dominance, fracture type, dislocation, reduction, and complaints with the plaster cast were recorded, and they were clinically scored for RSD. The follow-up lasted 1 year. FINDINGS: Eight patients were withdrawn after randomisation. 52 patients with 54 fractures (male 22%, female 78%; mean age 57 years) received vitamin C and 63 patients with 65 fractures (male 20%, female 80%; mean age 60 years) received placebo. RSD occurred in four (7%) wrists in the vitamin C group and 14 (22%) in the placebo group 15% (95% CI for differences 2-26). Other significant prognostic variables for the occurrence of RSD were complaints while wearing the cast (relative risk 0.17 [0.07-0.41]) and fracture type (0.37 [0.16-0.89]). INTERPRETATION: This prospective, double-blind study shows that vitamin C was associated with a lower risk of RSD after wrist fractures. Our hypothesis is that this beneficial effect of prophylaxis would be useful in other forms of trauma.
PMID: 10636366 [PubMed - indexed for MEDLINE]
|
from http://www.ncbi.nlm.nih.gov/pubmed/10636366
And this recent one:
Quote:
Foot Ankle Surg. 2009;15(4):179-82. Epub 2009 Apr 5.
Effect of vitamin C on prevention of complex regional pain syndrome type I in foot and ankle surgery.
Besse JL, Gadeyne S, Galand-Desmé S, Lerat JL, Moyen B.
Université de Lyon, Lyon, France. jean-luc.besse@chu-lyon.fr
BACKGROUND: The public health cost impact of complex regional pain syndrome type I (CRPS I) is considerable in both emergency and scheduled orthopaedic surgery. We proposed to assess the effectiveness of vitamin C in prevention of CRPS I in foot and ankle surgery. METHODS: We carried out a "before-after" quasi-experimental study comparing two chronologically successive groups without (Group I: July 2002-June 2003) and with (Group II: July 2003-June 2004) preventive 1g daily vitamin C treatment. All patients having surgery on the foot or ankle were enrolled, with the exception of diabetic foot cases. Several factors were analysed: sex, age, type of pathology, history of CRPS I, psychological context, tourniquet time, and cast immobilisation time. RESULTS: 420 feet (392 patients) were included in the study: 185 in Group I, 235 in Group II. CRPS I occurred in 18 cases in Group I (9.6%) and 4 cases in Group II (1.7%) (p<10(-4)), with history of CRPS I as a significantly correlated factor (relative risk=10.4). The psychological context (anxio-depressive state) showed a (sub-significant) tendency to increase the risk of CRPS I (relative risk=2.6). CONCLUSION: Vitamin C has been shown to be effective in preventing CRPS I secondary to wrist fracture, but few data are available with respect to foot and ankle cases. The present study demonstrates the effectiveness of vitamin C in preventing CRPS I of the foot and ankle-a frequent complication in our control group (9.6%). The authors recommend preventive management by vitamin C.
PMID: 19840748 [PubMed - indexed for MEDLINE]
|
The first study used 500mg daily for 50 days. The latter studies, and there are more than I have linked, used also 1000mg/day and 1500mg/day.
If your BIL is a diabetic, careful monitoring of blood sugar while taking high dose Vit C is advised.
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
************************************
.
Weezie looking at petunias 8.25.2017
**************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
|