Having had "incurable" neuropathy and see it disappear along with numerous other chronic conditions...I can say first hand the Marshall Protocol is valid...I believe it will become the model to follow in treatment of many different types of diseases caused by intra-phagocytic microbiota.Yes...you can dampen the infected and dysfunctional immune system and 'escape' the cytokine storm caused by stimuli such as a virus.....but the big elephant in the middle of the room is l-form bacteria that form biofilms and evade the immune system. Beta-lactam anti-biotics promote these l-forms by attacking their wall,some of the bacteria simply survive as cell wall deficient forms[l-forms]
They can only be studied in-vivo. It[the Marshall Protocol] is alot like the science that revealed that the earth is round, it will take some time before the paradyme changes. Medicine is so interpretive,and that's the only way it could be until now. Marshall Protocol comes more from an engineering and molecular modeling standpoint that is really more defined as definitive science.
It is not an easy treatment....as soon as you take the subinhibitory doses of minocycline,azithromycin,and clindamycin in a pulsed dose fashion along with a VDR agonist....{none of which have side-effects in healthy people}...you clearly feel the resulting herxiemer reactions.....and you know 25 milligrams of minocycline could not have produced such a reaction.......it's the little bugs...they start having their ribosome production shut down...and the immune system starts to kill what should have never been there. Meanwhile the VDR agonist allows the body"s own antimicrobial peptides to return to production[there are thousands of these]
Quote:
Originally Posted by kenki
I asked my specialist in Chronic Fatigue syndrome to comment on Marshal Plan claims that extra supplementation of Vitamin D results in shutting down the immune system altogether.
She replied as follows:
“I am familiar with the MP but I still don’t buy it! They talk about 25 D. This is not cholecalciferol – it is what the body chooses to make from CC. So unless there is overt deficiency of CC, it is a case of regulation – and I doubt that will happen simply through diet.
CC has so many important functions I cannot believe it is desirable to inhibit syntheses of 1CC and 1:25 DHCC by restricting sunshine and diet!
It’s all about the dose. In UK we are all deficient because of lack of sunshine. In Africa normal levels run at 100-150 – in UK normal range is said to be 20-70! My aim is to get levels up to the evolutionary correct levels.
It is highly protective against Swine flu”
She also attached an abstract from a research paper on Vitamin D:
Vitamin D is really important!
Skin contains a Cholesterol derivative, 7-dehydrocholesterol. UVB radiation on skin breaks open one of the carbon rings in this molecule to form vitamin D. The activated form of vitamin D (1,25-dihydroxyvitamin D) attaches to receptors on genes that control their expression, which turn protein production on or off. Vitamin D regulates the expression of more than 1,000 genes throughout the body. They include ones in macrophages, cells in the immune system that, among other things, attack and destroy viruses. Vitamin D switches on genes in macrophages that make antimicrobial peptides, antibiotics the body produces. Like antibiotics, these peptides attack and destroy bacteria; but unlike antibiotics, they also attack and destroy viruses.
Vitamin D also expresses genes that stop macrophages from overreacting to an infection and releasing too many inflammatory agents - cytokines - that can damage infected tissue. Vitamin D, for example, down regulates genes that produce interleukin-2 and interferon gamma, two cytokines that prime macrophages and cytotoxic T cells to attack the body's tissues. In the 1918-19 Spanish flu pandemic that killed 500,000 Americans, young healthy adults would wake up in the morning feeling well, start drowning in their own inflammation as the day wore on, and be dead by midnight. Autopsies showed complete destruction of the epithelial cells lining the respiratory tract resulting, researchers now know, from a macrophage-induced severe inflammatory reaction to the virus. In a terribly misguided way, these victims' own immune system attacked and killed them, not the virus, something in future pandemics vitamin D, in appropriate doses, can prevent.
A creditable hypothesis that explains the seasonal nature of flu is that influenza is a vitamin D deficiency disease. Cannell and colleagues offer this hypothesis in "Epidemic Influenza and Vitamin D" (Epidemiol Infect 2006;134:1129-40). They quote Hippocrates (circa 400 B.C.), who said, "Whoever wishes to investigate medicine properly should proceed thus: in the first place to consider the seasons of the year." Vitamin D levels in the blood fall to their lowest point during flu seasons. Unable to be protected by the body's own antibiotics (antimicrobial peptides) that this gene-expresser engineers, a person with a low vitamin D blood level is more vulnerable to contracting colds, influenza, and other respiratory infections (e.g., respiratory syncytial virus).
Studies show that children with rickets, a vitamin D-deficient skeletal disorder, suffer from frequent respiratory infections; and children exposed to sunlight are less likely to get a cold. Given vitamin D's wide-ranging effects on gene expression, other studies, for example, show that people diagnosed with cancer in the summer have an improved survival compared with those diagnosed in the winter (Int J Cancer 2006;119:1530-36)”I am not a scientist and could not comment. Is this useful?
Kenki
|