When I was hospitalized back in November for a crisis I was given this drug via an IV. My really, really bad double vision and breathing problems had not responded to 80mg of Prednisone (pill), so doc put me in the hospital to administer heavy steroids by IV. He knew my blood sugar would spike so wanted me monitored. The first night I had 500mg of Solumedrol in an IV drip. The next day I had 100mg four times injected into my IV line. After 3 days I got worse so he cut back to 40mg daily in pill form and I had a series of plasma exchanges. I didn't gain any weight (actually lost), but I try to adhere to a strict diet of low salt, low sugar, and low fat. The low salt is key when taking Prednisone.

I'm now down to 5mg of Prednisone and hoping to get off it in the next month or so.