Thanks Bobber for your great explanation. I have researched and have come up with the same conclusion. It makes total sense to me. I needed to hear someone else say it. I also have CRPS2. Originally had a few injuries and CRPS was missed(had all symptoms of CRPS and one Dr. suggested it before surgery but didnt follow thru). One injury was a major nerve entrapment so had surgery to decompress. After surgery it was calm while i did nothing, once PT started the CRPS spread quickly to all 4 limbs and face. (all the while ortho continued to deny it was CRPS!) All Drs. still think it is compressed due to the spread and pain at original site. Ortho asked if i want to do surgery again-she said new info reports if compression and have CRPS it is best to try to relieve compression. This does make sense to me. Pain Drs. say no way! Unfortunately it is a viscious cycle-how will it stop if the nerve is still compressed. Has anyone had surgery after knowing they had CRPS to relieve the original compression??? Maybe i could try ketamine right before surgery to hold me over from spreading. Please let me know. momof4