View Single Post
Old 02-26-2010, 08:24 AM
mrsD's Avatar
mrsD mrsD is offline
Wisest Elder Ever
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Hey, Bob!....

I've been going back to my grapeseed extract, after being reminded of it by another member here. I used to use it during allergy season mostly.

So I have been taking it starting at 100mg a day for a week, and now I am on 200mg a day... and my painful feet, which have been worse than usual with this weather, are MUCH better!

Today I decided to do a PubMed search on it, to see what new papers have accumulated there since my last visit, on this subject and found a TOOTH link. You may find this helpful

http://www.ncbi.nlm.nih.gov/pubmed/1...&ordinalpos=21
Quote:
J Nutr. 2009 Sep;139(9):1818S-23S. Epub 2009 Jul 29.
Grape products and oral health.

Wu CD.

Department of Pediatric Dentistry, College of Dentistry, University of Illinois, Chicago, IL 60612, USA. chriswu@uic.edu

Oral diseases, including dental caries, periodontal disease, and tooth loss, affect the majority of the population and can affect a person's overall health. Raisins contain polyphenols, flavonoids, and high levels of iron that may benefit human health. However, their oral health benefits are less well understood. We hypothesized that raisins contain antimicrobial phytochemicals capable of suppressing oral pathogens associated with caries or periodontal diseases and thus benefit oral health. Through antimicrobial assay-guided fractionation and purification, compounds identified with growth inhibition against oral pathogens were oleanolic acid, oleanolic aldehyde, linoleic acid, linolenic acid, betulin, betulinic acid, 5-(hydroxymethyl)-2-furfural, rutin, beta-sitosterol, and beta-sitosterol glucoside. Oleanolic acid suppressed in vitro adherence of cariogenic Streptococcus mutans biofilm. When the effect of raisins and raisin-containing bran cereal on in vivo plaque acidogenicity was examined in 7- to 11-y-old children, it was found that raisins did not reduce the plaque pH decline below pH 6 over the 30-min test period. Compared with commercial bran flakes or raisin bran cereal, a lower plaque pH drop was noted in children who consumed a raisin and bran flake mixture when no sugar was added (P < 0.05). Grape seed extract, high in proanthocyanidins, positively affected the in vitro demineralization and/or remineralization processes of artificial root caries lesions, suggesting its potential as a promising natural agent for noninvasive root caries therapy. Raisins represent a healthy alternative to the commonly consumed sugary snack foods.

PMID: 19640974 [PubMed - indexed for MEDLINE]
There are many new papers from 2009 in PubMed, using the simple keyword search "grape seed extract"... some regarding teeth, collagen and reducing inflammation from insulin resistance and diabetes II. All of them used high dose at least 300mg a day or more.
This looks very promising for PNers here with combined inflammation, diabetes and chronic PN pain!
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei

************************************

.
Weezie looking at petunias 8.25.2017


****************************
These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
mrsD is offline   Reply With QuoteReply With Quote