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Old 02-26-2010, 01:19 PM
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Diovan is less likely to have the cough.

All the ACE inhibitors can do this tho. It is due to an increase of bradykinin in the tissues. I had the most cough from Vasotec, but no cough with lisinopril or Accupril.

The lisinopril I think is the best one, of the bunch. It is not metabolized and is excreted whole, so it does not interact with other drugs or affect the liver. It has also been shown to enter the brain and reduce inflammation there, and is linked with a decrease of Alzheimer's potential. There are some studies showing it benefits MS patients too.

Kitty, you might try breaking it in half and taking 1/2 in the morning and 1/2 at night. What dose do you use? In the lower dosage range breaking in half is probably not going to make much difference. Lisinopril has a long half life, anyway, so splitting the dose may reduce the side effect a bit.

This article is interesting --near the end it gives potential things to try... If you know you are low in iron...this simple thing may help. Also aspirin, but long term use of that can cause bleeding, of the GI tract. The connection to arachidonic acid etc, gives me a clue that fish oil may help you too. It is not mentioned in the article, but it is a Cox-2 inhibitor as well. I use fish oil and consume salmon and other foods with it added, so maybe that is why my cough is less than it used to be back in the Vasotec days!
http://www.medscape.com/viewarticle/484537_2
(if you can't view this, you can join for free...very easily).
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Kitty (02-26-2010)