I take Rituxan, but not for PN. I take an 860mg infusion of Rituxan every three months for Waldenstroms cancer. For my PN, I take 1800 mg of Gabapentin daily, along with Metanx in the morning, and 50 mg of Nortriptylene at night.

This combination seems to relieve the pain of PN pretty well, except when the IgM in the cancer takes a notion to spike up. When that happens, the PN pain goes up with it. My PN is a outgrowth of the Waldenstroms, so as long as the IgM is soaring (presently at 6,400, should be 350 ) the pain from the PM is soaring right along with it.

Talk to your Dr. about the Gabapentin, and the Nortriptylene. They seem to curb those deep pains pretty well, at least for me.