My doctor perscribed Effexor to me also for depression, he said I could not have received a concussion because I didn't get knocked out, and all my symptoms were depression related. In my opinion, Effexor is a terrible drug. The withdrawl effects are unbearable, I couldn't beleive FDA would approve a drug with such horrible withdrawl symptoms. If I went over a day without taking a dose, it gave me nasty headaches, irritability, and horrible anxiety. I then switched over to zoloft which I actually had no problems with, and would recommend to anyone who suffers depression/anxiety from PCS.