Looks like they found dimebon in a way similar to amantadine. But they don't think the antihistamine was what caused the improvement in alzheimers patients. It is an old allergy drug.

here is a direct link to the announcement and article

http://finance.yahoo.com/news/Pfizer...16347.html?x=0

i couldn't help but notice that olsen posted this trial failure and i read it and went to the link and the news was just posted 14 minutes prior to my getting there. this forum is so on top of it. anyway this one is not a cholinesterase inhibitor so i hope they don't give up on it. somewhere i read - maybe in Olsen's article, that one person said," you don't give up on it just because of one failure." UH.....ye...ah!

adding question: do people with alzheimers have a placebo effect? can they? this was late stage alzhheimers but with cognitive loss could you still have the placebo effect. note that they say this didn't work with either group. with pd they all work.....wondering.

Yet in the final-stage study, which included 598 patients with an average age of 74, symptoms didn't subside in either patients getting Dimebon or those getting dummy pills.


paula
another article from 2008
http://www.rxlist.com/script/main/ar...ticlekey=88934