I dont know what meds you are on but some can deplete the body of essential nutrients because they block the absorption or just change the way the body uses it. Calcium/magnesium supplements are enough for me to ease mild cramping and when I get that funny tingly numb foot falling asleep thing I make sure I've had my B12/folic acid. I found out I don't absorb and use the more commonly sold B12 with the cyanocobalamin(sp?). I take the Methyl formula and I see a huge difference in energy and tingly stuff. All this helps, but Im not saying I have left conventional medicine behind me, I just pay attention to my nutrition before I ask for dose changes or different meds altogether. Hope it helps.