Thanks Cyclelops, the test results are indeed a relief being the panel of tests that were run were for amyloidosis, small cell carcinoma, etc... so it is definitely good that the panel was negative.

And yes, I have had a +speckled ANA 160 (not particularly a strong positive) in the past (last few were normal) and often have a +sed rate and elevated immunoglobulins. I have had, for many years, vague symptoms of autoimmune illness but never have tested positive for anything definite (and may never).

...Sometimes referred to as undifferentiated connective tissue disease and I also have arthritic problems with my joints (especially large), so Rheumy also diagnosed me as having spondylarthropathy. I take a DMARD (Humira) and it helps with that. I do not have antibodies for Sjogrens but have vague symptoms such as dry mucous membranes.

I have several neurological symptoms, but with all this testing, the only positives are sed. rate at 36 and "moderate" small fiber neuropathy through skin biopsy and neuronal (?) weakness (shows physically and on nerve conduction study). I have never had any autonomic testing done.

The gastroparesis started last summer after a particular bad episode of dysautonomia. The dysautonomia started about the same time as the AI symptoms - about 17 years ago following a particularly bad viral pneumonia. It started suddenly and severely. I had spells of tachycardia, syncope, asthma, flushing and paleness, bladder problems, severe weakness and severe weight loss. The dysautonomia has improved somewhat over the years and then returned as "attacks" - some of the symptoms have changed a bit (asthma is gone), but some are the same. I always have the flushing with congestion. I really wonder if I had Guillan Barre 17 years ago when this all started...I remember being so very ill for so very long.

I am, as many are, frustrated with a lack of a reason for the PN. Neurologically, things are progressing - slowly, but surely. It concerns me.

I suppose my experience with PN is a common situation - quite possibly referred to as 'ideopathic". I will see the specialist as recommended...

Mere