Here is a monograph on alpha lipoic acid.
http://www.umm.edu/altmed/articles/a...oic-000285.htm
The studies used pretty high doses and there are many on PubMed.
The most significant thing in the high dose range (and this monograph goes to 800mg a day) is potential lowering of blood sugar. This may or may not happen, but diabetes using insulin and/or oral drugs should be aware of this potential.
The comment about thyroid is based on ONE study of rats only, and as of yet there are no studies involving humans.
R-lipoic is more potent but works the same way. Alpha lipoic is a mixture of two forms of lipoic acid... one left handed and one right. The body can only use one form to fit the proper enzymes, so the other form is thought to be useless.
This is complex, but you can read about it here:
http://en.wikipedia.org/wiki/Lipoic_acid
R- form has recently become more affordable and available, and some people use it instead. Typical doses for it are 100mg a day.
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
************************************
.
Weezie looking at petunias 8.25.2017
****************************
These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.