I have had RRMS for over 20 years. I have pain in my hands, along with cramping and numbness, which got worse over time but has been the same for a while now and I've been on Nortriptyline for years for it. I also expierence pain in my right leg, which has gotten worse these past few years. Fortunately it's not to the point where I feel medicine is necessary (or I'm just being stubborn). Not sure if my story helps you or not, but I hope it does.