The problem with statins is across the whole family. Simvastatin is very lipophilic and goes into nerves and the brain more than some others. But the damage is done to the mitochondria in the cells. These little factories make energy for each cell and when they cannot the cell dies or cannot function normally.

This subject is becoming HUGE. There are many serious issues now with statins. And your dose is the largest typically used besides. What was your cholesterol before taking them? Over 300? You need to discuss your need for this drug at this dose with your doctor. If you have extremely high cholesterol over 400, due to familial inheritance, there is no getting around it.
Lovastatin may be milder for the PN effects, but they all cause it. All statins deplete CoQ-10 from the body. The mitochondria use this to transport fatty acids. The same enzyme that makes cholesterol makes CoQ-10. When CoQ-10 gets low, your heart suffers and you may develop weak muscle and cardiomyopathies. That is something doctors do not tell you, so you can help prevent it.
Dr. Graveline MD is a former astronaut who lost his memory on Lipitor. He has a large website he made after he recovered, and you should visit and read. Here is his statement on CoQ-10:
http://www.spacedoc.net/statins_CoQ10.htm

Here is a recent link with some links listed...please read them carefully:
http://neurotalk.psychcentral.com/sh...ghlight=statin

George and Stagger both have PN connected to Zocor.

If you visit PN forum and search "statin" you'll find many many posts!

The empty stomach suggestion for B12 means about 1 hour before FOOD. You can drink liquids with it, but I wouldn't have cream in them. It is the solids and fiber that bind the tiny microgram doses of the B12 and may limit its absorption.

And yes, you may not even need the P5P if you get results without it. B6 is a strange nutrient, because when very low you get neuropathy and when VERY high --in the 500mg to gram long term range you also get signs of neuropathy. There have been a small number of people who claimed that 50mg a day bothered them, but I don't really buy that. So just try to stay under 50mg a day average, just because people do vary so much.

The tingling should stop and slowly reverse. If you are getting neuropathy from your statin, you have to stop it, or face potential lifetime loss and pain. You are lucky you only have tingling so far.

There are other things for diabetic neuropathy:
Alpha lipoic acid
Acetyl Carnitine
CoQ-10

You also need a Vit D test, to see if you are low: Vit D can be low in diabetics and others with chronic disease/pain. Fixing those levels, helps tremendously:
Please watch the newly presented medical videos here:
http://www.grassrootshealth.net/

I think I covered it all for now? Seems like a bit of homework for you to do, doesn't it?