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Old 03-16-2010, 04:20 PM
LarP LarP is offline
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Join Date: Feb 2010
Posts: 8
15 yr Member
LarP LarP is offline
Junior Member
 
Join Date: Feb 2010
Posts: 8
15 yr Member
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hey mrs D - a reply from me in 24ish hours - see my comments below, after yours, in blue

The problem with statins is across the whole family. Simvastatin is very lipophilic and goes into nerves and the brain more than some others. But the damage is done to the mitochondria in the cells. These little factories make energy for each cell and when they cannot the cell dies or cannot function normally.
This subject is becoming HUGE. There are many serious issues now with statins. And your dose is the largest typically used besides. What was your cholesterol before taking them? Over 300? You need to discuss your need for this drug at this dose with your doctor. If you have extremely high cholesterol over 400, due to familial inheritance, there is no getting around it.
Lovastatin may be milder for the PN effects, but they all cause it. All statins deplete CoQ-10 from the body. The mitochondria use this to transport fatty acids. The same enzyme that makes cholesterol makes CoQ-10. When CoQ-10 gets low, your heart suffers and you may develop weak muscle and cardiomyopathies. That is something doctors do not tell you, so you can help prevent it.
ok, I really need to discuss this with my diabetes doctor . . . unfortunately I don’t know how high I originally was, but I don’t think I was over 400 and/or my problem is from inheritance - but I do know that I really am watching my diet these days (lots of salads, veggies and lean proteins) and swimming at least 40 minutes 3 times a week, so I assume it’s dropped quite a bit naturally – net net, on my next doctors visit I will get my blood tested for this and discuss it with him, but for now, I may just stop using this med and contact him about it
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The empty stomach suggestion for B12 means about 1 hour before FOOD. You can drink liquids with it, but I wouldn't have cream in them. It is the solids and fiber that bind the tiny microgram doses of the B12 and may limit its absorption.
Ok, I can do this in the AM, thanks for the clarification

And yes, you may not even need the P5P if you get results without it. B6 is a strange nutrient, because when very low you get neuropathy and when VERY high --in the 500mg to gram long term range you also get signs of neuropathy. There have been a small number of people who claimed that 50mg a day bothered them, but I don't really buy that. So just try to stay under 50mg a day average, just because people do vary so much.
Since my Puritan Pride One tablet is already at 50 mg, I will skip the P5P


The tingling should stop and slowly reverse. If you are getting neuropathy from your statin, you have to stop it, or face potential lifetime loss and pain. You are lucky you only have tingling so far.
Agreed

There are other things for diabetic neuropathy:
Alpha lipoic acid
Acetyl Carnitine
CoQ-10
As per a previous response in this thread (I understand you are a very busy here!), I want to wait until I get more familiar with my next set of pills before I add any more

You also need a Vit D test, to see if you are low: Vit D can be low in diabetics and others with chronic disease/pain. Fixing those levels, helps tremendously:
OK, I will talk to my doctor about this, but isn’t the dosage of Vit D in my Purtian One tablet good enough (Vitamin D - as Cholecalciferol) 400 IU) . . . and before that, I’ve been taking their ultra vita-min pills for years (which would have at least the same Vit D in them)

I think I covered it all for now? Seems like a bit of homework for you to do, doesn't it?
No probs – for my health, it’s all worth it – I will order my vitamins this evening – as always, many thanks again for all your help
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"Thanks for this!" says:
tamiloo (03-21-2010)