I was on Zoloft and Effexor and amitryptelene all at once. Started with the Z which did nothing then switched to E again with no result, then they combined the 2 which helped take the edge off but made me jittery, then they added the A to help me sleep. The A turned me into a zombie, and the other 2 really didn't do much by way of stopping the panic attacks.

The one I am on now, Cymbalta works great on stopping the panic attacks. The problem is, I refuse to take it every day, because I don't feel that I need it every day, and after taking it for about a week I tend to be a real "B" for 2 days after stopping.