(((Dej))) It is a trial and error type of thing. I take an AD as part of my pain management regime. They started me on Cymbalta, which worked awesome for pain, but NOT my emotions. I am a passive, calm (unless in pain - then I get anxious) type person. By the 3rd day I was having aggressive type thoughts. Scared the carp out of me. No more Cymbalta for me.

Next up was Paxil which worked great for a little while. Then my affect went flat.

I now take 5mg - 10mg (alternating days) of Celexa (generic). It works ok, not quite as well as Paxil for keeping me calm during painful times.

Also, there are a few groups of AD's and each work on different synapses and neurotransmitters within the brain. Cymbalta is a SNRI while Celexa and Paxil are SSRI's, which could explain why Cymbalta did not work for me. This is a link to a fairly good article on different ADs and how they work. If you want an more in depth one let me know.

http://users.rcn.com/jkimball.ma.ult...ntidepressants

Hang in there, Dej and know that we are here to help you through this.