Letting strangers into your home is a concern.
I rented out rooms in a house in two different places at two different times. I almost always had two separate roomers, often three, and got them by placing ads.
I checked their references and often met family members. They weren't allowed to have visitors, smoke or drink on the premises, but I kept the rent low and could offer them off-the-street parking. I never had a problem finding roomers.
Nobody ever gave me any big trouble. A couple of people were asked to leave but it was because they were breaking rules.
One did skip out leaving a note saying he was wanted for murder. I never did find out if that was true but I did find it a bit unsettling....
If you rent to more than one person at a time, the chances are that each one will behave because the other is present. Also, you have neighbors and people you know who might happen in at any time. At least you do unless you live in an isolated area but I didn't.