Hi Rose- I just want to double check with you as I know you are expert on this. I had very low B12 and neurosymptoms (dizzyness, parasthesias, decreased left hand function very min cognitive change) dxd in fall 2004. I had frequent B12 injections until recovery (no more dizzyness, very mild parasthesias). Then we went to 1,000 micrograms via shot 1x per month. Last fall I had a very slight increase in symptoms and my doc upped this to 1,00 micrograms 2x per month. The doc is worried this may be "too much" and I am worried that if we reduce it my myelination may decrease/symptoms may return. Do you know if there is any research about the effects of a high dose of B12 given over time and long term impact?

Ill look forward to your advice. I hope you are well.

Sincerely, Rachel Hitch