Immunotherapy for Parkinson's disease: Mechanisms and pathways for human use
Authors:
Howard Gendelman, MD, Chairman and Professor, University of Nebraska Medical Center
R. Lee Mosley, BS, MS, PhD, Associate Professor, University of Nebraska Medical Centerimm
This finding is analogous to the untoward T cell-mediated meningoencephalitic responses observed by amyloid beta immunization (Morgan et al., 2009). Adding credence to this notion is the fact that reported that T cell responses elicited during the course of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxication led to accelerated neurodegeneration (Theodore et al., 2008).
http://www.pdonlineresearch.org/resp...ways-human-use