I was pretty much sx free in the 80s, but since 1992, I have constant sx. Some days worse than others, depending on the weather or my state of general health, at the time.
I have a general numbness, tingly feeling all the time, now, but LDN has greatly minimized that.
When I have a cold or am stressed or the weather is humid and/or rainy, it's almost like having a flare, but it goes away when the situation changes for the better.
Inflamation/infection of any kind is our enemy. Sometimes, if I take a couple of Asprin, I improve....get it - anti inflamitory?