Zyprexa is an antipsychotic. It's used to treat schizophrenia, bipolar depression and stubborn depression that doesn't respond to other meds. I know it effects serotonin and dopamine levels, but I'm not sure how. I'm guessing the way it works for RSD might be similar to Cymbalta or the old school antidepressants like Elavil and Nortriptyline (?spelling). The chemicals effect nerve impulses and we have screwed up nerve impulses.

I know it was one of those drugs that the side effects list scared the heck out of me .........will increase blood sugars in diabetics and possibly give you diabetes if you didn't already have it, increased cholesterol levels, massive weight gains, seizures, etc..........and those were just some of the side effects that don't instantly kill you.

Neurontin increases my blood sugars and gives me brain fog but I still take it. My husband thinks Cymbalta made me psychotic (a possible side effect) just because I asked for a divorce.....he didn't think our 10 year sexless loveless marriage had anything to do with it ............So sometimes we need to take meds with side effects or possible ones that we would prefer not to have, but I don't think Zyprexa is the magic pill that will fix all of us like we would like.

I believe this Zyprexa success story is like Neurontin/Lyrica helping some people a lot, some of us it helps a little, and others can't/won't deal with the side effects.

Coach......I'm so happy for you ! Alleviating RSD symptoms sure is a great side effect for a drug that your body needed anyhow ! Thanks for posting this. I had never heard of Zyprexa having an effect on RSD sx's before.

I still have my fingers crossed for the one magic pill or wave of a wand that will fix us all !