Sandy, you didn't mention if you give Jim something like ibuprofen before giving the Beta. I ask because if I don't premedicate with ibuprofen or acetaminophen, about 3 to 4 hours after the injection I get this overwhelming urge to stretch and when I do my back and side muscles give me fits. Immediately after that I have uncontrollable chills, but no fever. I did the same thing with Copaxone.