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Old 04-06-2010, 07:04 AM
glenntaj glenntaj is offline
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Join Date: Aug 2006
Location: Queens, NY
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glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default Neuropathy is a VERY common secondary affect--

--in most of the major vascultic/connective tissue autoimmune anti-nuclear-antibody diseases (he wrote, adding to dahlek's list of links to the Washington University Neuromuscular Disorders website):

http://neuromuscular.wustl.edu/antib...tml#vasculitis

And, there are other autoimmune situations that attack nerve directly, such as developing natibodies tonerve components such as sulfatide or myelin associated glycoprotein.

In vasculitic/connective tissue disorders, one can have neuropathy from multiple mechanisms--the breakdown of blood vessels may hinder the nerves getting nutrition and oxygen and eliminating wastes, or, the compressive forces on them from connective tissue changes may damge them, or the drying out of mucous membranes may make it harder for normal chemical reactions of metabolism to be carried out.
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"Thanks for this!" says:
dahlek (04-06-2010)