During a really bad stomach virus, I didn't take ANY mestinon AT ALL for almost two days. I'm normally a 6-10 pill a day gal. I "survived" without my Mesty -- didn't have much of a choice -- although a doc in another group told me that I could have tried to take it vaginally.

My neuro has given me total freedom to regulate my dose -- up to 10 per day. I start off with 1 1/2 (90mg) first thing in the morning. Usually take my second dose 3 hours later -- but, I may take it earlier or later -- depends on how my mouth is working. I'm "puckering" all day long -- that's how I check to see if it's time to take more Mesty -- works better for me than the clock.