I take 50 mg./day of Baclofen although some people are on far higher doses with implantable pumps, something we share with the MS community.

However, my secret weapon is Marinol, which comes in 5 mg. gel caps. It's an off-label use for a synthetic version of one of 9 naturally occurring THC molecules in cannabis: its approved use is in combating nausea, and improving appetite, especially after chemotherapy. For particularly bad spasms I am prescribed 2 at a time. It takes about 40 minutes to become effective, although I have heard that it may be possible to smoke them in a glass pipe, for immediate relief. But even having to wait 40 minutes or so, it’s the most effective medicine I have ever had for these CNS induced spasms. Of course, Marinol cannot be used while driving, etc. The good news is that, if I take it in the evening, I am completely clearheaded by morning.

Mike