I have been taking CDP Choline (also called citicholine) now (250mg to 500mg per day), along with my curcumin for 5 years. I recommended the two supplements a number of times on the old MGH site.
I have now found that not only curcumin reduces the permeability of the BBB, but so does citicholine. A good review of citicholine is at
Citicoline: The Brain Protecting Choline Supplement
http://www.naturalproductsinsider.co...ngredient.html
I took citicholine since it is given to stroke victims in the UK, and is said to assist brain metabolism. I did not know it also had a beneficial effect on the BBB. One bit of bad news, I don't think it is approved in the USA.
Ron