Yes. I heaved non-stop while in the hospital with a fractured skull.

The year being 1966 in a rural hospital they just let me retch and gave no meds or IV fluids. I couldn't even keep a sip of water down. This resulted in dehydration and made my splitting headache (pun intended) a great deal worse.

To this day I shudder at the sight of orange jello. That was the first solid food I could keep down but it took another couple days before it stayed down.

I rather hope treatment of a fractured skull has improved since then.