I have problems with things aching too, however, that said, aching calves can be another problem...intermittent claudication.

I don't know your age or cardiac profile, but, it may pay to let your doctor know that your calves ache badly.

I have very bad RLS too, but had that way before any aching....Who knows when the PN started??? Could have been decades before diagnosis. I use Mirapex for the RLS but mine is RBS...restless body syndrome. I have it in legs, arms and upper back.

Now I have an at risk cardiac profile and the calves often hurt....I just reconnected with the cardiologist.

I also have autoimmune issues too. Just fallin' apart here.