Cramps, muscle spasms charliehorses, whatever you call them, are my worst symptom. They were one of the first symptoms many years ago, but when I got on medication they went away only to reappear in the past couple of years. They are worst when meds are waning and corelate to movement in my hands. If I an doing something with my right hand my left foot will begin to curl under until I can't stand on it. I also get spasms in any muscle I stretch first tthing in the morning.

I have been told it is dystonia and more responsive to agonists than to sinemet. Meds worked when I was on an agonist alone but did not work on sinemet alone. They worked for a while on both but stopped after a year or so. The addition of Amantadine has helped for the past 9 or 10 months but is starting to lose effect now. Don't know where I'll go next. Maybe Botox.

Good luck,
Pam