I was on Avonex and then Cpaxone for about 10 months. I stopped Avonex because of the side effects...I stopped Copaxone because it just wasn't working.

As soon as I went to SPMS, I stopped all poisons.

That's the thing that hurts me the most about being SPMS, there are no healing meds being produced that fills our need.

LDN helps me a lot and I love it, but it isn't a cure and will not make my MS go away. None of the DMDs are going to make it go away either, but, at least I feel better with raised endorphines. I was sick constantly while on the CRABs..

It's much easier to find a med for RRMS, since it is, in the early days, self healing, so they can say...AHA, it's working..

If the DMDs do their job and stop your MS from progressing to SPMS, then and only then will any of them be worth a ****.