I was on betaserson for two weeks. When I increased the dose to 50%, I had a nasty allergic reaction. So the neuros said no more interferons. I was then on copaxone for 4 1/2 months. Had six IPIR's in that time accompanied by high temperatures, cold chills, and shaking. Next in my first year journey of MS was tysabri. Had 5 infusions and experienced increasingly severe infusion reactions.Also developed antibodies I decided to try copaxone one more time. On the very first day, I did not have a IPIR but about three hours after the injection my temperature shot up to 103. So both my neuro and shared Solutions decided that was rather unusual and I was told to stop injections. So that is my experience with DMD's. The next step in my journey will probably be whatever oral med is approved first. On the other hand I have been stable for the past two years -- so maybe not!