My first DMD was C. I stuck with it (no pun intended! ) for a year but it wasn't helping me. My MRI showed more lesions. From that I went to Betaseron. The side effects were terrible and my next MRI showed more lesions. I decided to go off of all DMD's and give LDN a try. I felt so much better within just a few days of beginning it. Like Sally said, it's not a cure and shouldn't be thought of as one......but it certainly made me feel better. I have learned throughout this journey with MS that I know my body better than any doctor or specialist does. I listen to them and then make my own decision about which meds to take and which ones I don't want to subject myself to. Guess I got tired of being a guinea pig. I really don't care if my Neuro thinks LDN is a viable choice in my fight with MS. It works for me and that's all that matters.