Hi I have flown a lot with this. A few things that have helped me is to make sure I get up a few times during the flight. When I get stiff and cramped the pain sets in and is hard to settle down. Proper clothes cause I am sensitive to cold and that too increases pain. I take a wheel chair to and from the gate. For me it would be too much to walk cause sometimes it is so far. I am not sure about the pressure of the cabin but for me it is stressful to fly cause I don't know how I will feel and it is a long day. A person without pain or health problems talks about being tired after a day of travel so for us it is even harder.