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Old 06-18-2010, 08:51 AM
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
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This is from the iherb link:

Quote:
(State of California Prop 65) This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.
I am now going to have to see which of these ingredients is the culprit.

Yohimbine: from http://healthlibrary.epnet.com/GetCo...chunkiid=21892
(iherb's link to the Natural Pharmacy)
Quote:
Safety Issues

The following discussion applies to the drug yohimbine, rather than the herb yohimbe. All risks of the drug apply to the herb, and there are additional risks to consider as well. For example, as noted above, the amount of yohimbine in a given sample of the herb may not be accurately reflected on the label.16 Furthermore, additional constituents contained in the herb besides yohimbine might present unique (and unknown) risks of their own.

Yohimbine in any form should not be used by pregnant or nursing women, or those with kidney, liver, or ulcer disease, or high blood pressure. Intake of more than 40 mg a day of yohimbine can cause a severe drop in blood pressure, abdominal pain, fatigue, hallucinations, and paralysis. (Interestingly, lower dosages can cause an increase in blood pressure.) Since 40 mg is not very far above the typical recommended dose, yohimbine has what is known as a "narrow therapeutic index." This means that there is a relatively small dosing range, below which the herb doesn't work and above which it is toxic.

Even when taken in normal dosages, side effects of dizziness, anxiety, hyperstimulation, and nausea are common.

Finally, yohimbine may interact adversely with numerous medications, including tricyclic antidepressants, buproprion, methamphetamine, phenothiazines, clonidine, and other drugs for lowering blood pressure.5-14,17
This is a more comprehensive link with side effects listed:
http://www.webmd.com/vitamins-supple...HIMBE&source=2

Tribulus has these warnings about regular use and prostate health:
http://www.webmd.com/vitamins-supple...+VINE&source=3
But it might be the Tribulus and prostate effects.

There is a warning concerning Ashwagandha extract and the thyroid. I wonder why this is in this product, in fact.
http://www.webmd.com/vitamins-supple...ANDHA&source=0
Since this product increases the immune system, it would not be a good choice for PNers with immune mediated PN. This herb is typically contraindicated for MS and MG.

I could not find which ingredient is not approved by the State of California at this time.

It is a good idea to research herbal products before taking them.
Herbs can be complex, and act as drugs, and interact with other drugs you may be taking. Research the manufacturer and make sure the herbs are tested for impurities before they are used to make any product. China and India have had reports of contaminated products over the years. Lead is the usual culprit, but China has been known to lace their herbal extracts with REAL drugs! So beware of Chinese sourced products.
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