My husband has had many red cell and platelet transfusions but his PN is drug related. We know many who have had multiple blood products as a result of bone marrow disorders that never got PN from it. So I would venture to say there is not a connection. Red cells are closely matched so that you don't have a reaction, but over time, after multiple transfusions, your body can develop anti-bodies to blood products. That's why they cross and match your blood to the blood they are planning to use for your transfusion. They check for more than just blood type.

Marlene