You have my empathy, for sure.

I'm struggling with that issue, also, and add into the mix a personality that constantly asks "what if? what if?" Especially, "what if I make the wrong choice and REALLY screw up my life??"

I still say it's a crap shoot, mainly because the disease IS so unpredictable and individualized.

My Dad had MS over 40 years, never took an MS drug, never ended up in a wheel chair. BUT! I grew up under "Tomorrow might be the day your father wakes up and can't get out of bed." I think of that stupid tv ad for some drug, the one where the stretcher follows the guy around, waiting for him to have another heart attack.

Copaxone was (apparently) causing me debilitating anxiety (and yeast infections--I'm sure it wasn't a coincidence). I took an "unauthorized" break, and my neuro wants me to try again, see what happens, re-evaluate in three months.

I look at those stinkin' needles, and I either see a miracle that I should be accepting, or a snake ready to strike. I keep telling myself, just give it a try. Then: cluck cluck cluck. I get anxiety thinking about the anxiety.