LDN has helped me too. Many improvements, even old residual damage is gone. Can the other drugs do that? I don't think so. No progression, and I was progressing prior to LDN. I am taking 3.0 mg at bedtime, with a glass of water. I wish I had a set bedtime but I don't, so I take it about 1/2 hours before shutting my baby pale greens. Lol

I may go to bed at 1, 2 or 3 am. Just take it before going to sleep, no later than 3 am is okay Skip said to me, but that is the time I told him I may go to bed if I nap during the day. I never asked about 4 or 5 am. But I think we make our endorphins around 3 am, but we are all different.

I don't take Prozac or any anti-D's. I never needed them. But I'm sure it won't hurt you if your body needs them. LDN lifts my mood a lot.

If life is harder on you, or you're missing, or low, on a chemical in the brain that's helps you avoid the high and low's of the day, or stressful situations, then anti-D's is the way to go.

Eddie, if you moods are steady, and you never feel that dark cloud over your head, or you can see the light at the end of the tunnel on a bad day, then maybe you do not need the chemical booster of anti-D's.

No two people are alike in this world, and the same with MS and other diseases. We try meds and pray they work for us.