Thread: Levodopa pumped into bowel??
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Old 02-04-2007, 01:59 PM
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reverett123 reverett123 is offline
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reverett123 reverett123 is offline
In Remembrance
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Quote:
Originally Posted by rd42 View Post
This may be an ignorant statement, but wouldn't it be cheaper and easier to, well, uh, stick it where the sun don't shine?

I wonder if there would be better absorbtion in the colon than in the stomach?

Robert


But that is a very good question. If I understand correctly, there are two problems with the stomach: lack of absorption and degradation by enzymes. I am sure that the colon-rectal absoption is good or there would be no suppositories. One might even try an enema vehicle with a crushed tablet. But the controlled release or standard, I wonder? And might there be something that enhanced absorption as well?
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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