those b12 niumbers just show the b12 that is in the blood, not in the tissues. if you take a b12 supplement you may well go off of the scale that they use to measure it in the blood. It wont hurt you. excess is just flushed out of the body. mine is off the charts also but i keep taking it to help provide the conditions in which healing may occur, even after so many years i havent given up yet.