I wonder....?
It is now known that SSRI drugs (serotonin reuptake inhibitors) over time, downregulate dopamine in the brain. I don't think this is well understood yet, but it appears that the brain senses the excess serotonin and tries to compensate and that involves dopamine. SSRI patients often develop movement disorders of the jaw, face, and tongue that resemble Tardive.
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Stimulation of postsynaptic 5-HT2 and 5-HT3 receptors decreases dopamine and norepinephrine release from the substantia nigra. A number of drugs are not associated with sexual side effects (bupropion, mirtazapine (Remeron), maprotiline (Ludiomil),[31][32] (some of these are also not associated with weight gain). As a result, sexual dysfunction caused by SSRIs can sometimes be mitigated by several different drugs. These include:
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from
http://en.wikipedia.org/wiki/Selecti...take_inhibitor
The brain seems to have some internal balancing system regarding neurotransmitters.
This seems analogous to the transplanted cell excess of serotonin in these PD cases.
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Weezie looking at petunias 8.25.2017
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