I changed the time that I take my LDN from around midnight to around 3AM and I seem to be responding to it with more strength and feeling.
I didn't do it on purpose, at first. I fell asleep early and didn't awaken until 3AM. My body liked the change, so I continued it.
I'm thinking that there is probably a perfect time for each of us, between 10PM and 4AM, and my time is 3AM.

It was working fine at midnight....just a bit better at around 3AM!!
I guess my endorphins are doing their thing and LDN is doing it's thing at about that time, in my body.