Wow, Sherri, I didn't know gabapentin had that side effect. I have been taking 600mg for almost 10 years. But, I only take it once a day before bedtime.

Early on, I had a bowel bloating problem but it seemed to be tied to my TOS. My ileocecal valve (between small and large intestine) would spasm closed. It took me six months of laxatives to get my system working correctly. My PT helped a lot. She could manually release the spasms. My concussion came with some trauma to my neck, especially C-5, C-6, C-7 and T-1, where TOS manifests most commonly. I did not change my gabapentin use during this time. I was taking 600 mgs at 10 pm each day. Now, I take 900 mgs at 10 pm.

Keeping my back in good shape helped with the bloating.

In women, their bowels slow between ovulation and menses to provide more nutritional digestion in case the woman is pregnant. You might try observing when your struggles come if they return.

Gabapentin only has an 8 hour half life. That means that 50% is out of your system in 8 hours. 50% of the remainder is gone in the next 8 hours, and so on. The build up in your system with twice a day may have been the key to your problem. You never had a let down in gabapentin concentration in your system.

My best to you.