Hi Ann,
I don't have RLS but I do have PD. I thought this may be of some help to you. At one point in the medication change game, I switched from Requip to Mirapex. I titrated down off of Requip completely before starting Mirapex. My reason for switching between Requip and Mirapex, weight gain, constant sleepiness, and cloudy thinking. Any positives from changing? No,none. Any negatives from changing? Yes, sleepiness became worse, weight gain became worse, cloudy thinking became worse, OCD urges grew significantly. I finally titrated down off of Mirapex and have never taken either again.

GregD