I wonder if there is a lack of availability of TEMs (transmission electron microscopes)? And that is why there are not as many sites for skin biopsies? They are not just found everywhere and need particular support lab equipment and technicians. But I think I have heard of results being done by other microscopes, however the details with TEM are more "detailed".

I'm a retired EMer so am prejudiced and a new member here who also had a skin-punch done but didn't know about the EM connection at the time...it has been good having those results to back me up several times and just for peace of mind. My own EM work was for 17 years but on viruses...we did have some chronic fatique work to do but nothing on FM when I was doing it. But I left that work 14 years ago. (I don't recall seeing anything in the CFS samples we had.)