I have had adverse reactions to Lipitor (my doc is sold on its benefits, but not receptive to the literature on its negatives) from the first month on it and demanded that my doc switch me to a non-statin, if she really felt it necessary for me to have low cholest. numbers.
I recommended Zetia (suggested to me, by MrsD) and have had success with it for about 4-5 years, now. My Rx insurance plan continues to try to get me to switch to a lower cost statin, and I have to get my doc to submit a waiver for me, about every 6-12 mos.- but I won't go back on a statin.