While I appreciate the post here, I do wonder why they keep recycling things as if they are new discoveries. ALL of this information was previously published years, yes years, ago, in an article by a mayo clinic doc (can't remember his name and don't have the article) called "Beating a Dead Horse".

The article was basically saying that dopamine is NOT all there is to PD, and researchers need to recognize that and start looking at the other things that manifest years, often decades, before motor symptoms appear. It was a fabulous article and the only one our neuro has ever given to us (I guess we're on about a 50:1 ratio, for every 50 or so articles we give him, we get one!). But it was good, and said all the things this article says.

Sorry to poo-poo this, it's just that the article our neuro gave us was written in 2007, three years ago....now here's the same information and what has been done with this information/"discovery" during those three years? No wonder things take so doggone long, it's so frustrating.