Madelyn,
Does this statement mean that this slow metabolism allows acetylcholine to build up ? And they have associated that with early onset pd?
"Polymorphisms in the Phase II activity of N-acetyltransferase can also lead to slow
metabolizers. Associations have been found between slow metabolism through the Nacetyltransferase pathway and high risk of some types of cancer and Parkinson’s disease.
5,7,10
Polymorphisms in Cyp2D6 have also been associated with a high risk of early onset Parkinson’s disease."